MPB series
Parallel bioreactor
"Scientz · Main Yuan" MPB series parallel bioreactor is jointly launched by Scientz Bio and East China Science and Technology Entrepreneurship Team. The core R&D personnel graduated from East China University of Science and Technology, Shanghai Institute of Biological Sciences of Chinese Academy of Sciences, Zhejiang University and other institutions of higher learning. They have been engaged in fermentation process research for a long time and have rich experience in reactor design.
The product can help experimenters to efficiently evaluate the influence of different culture strains and process parameters, quickly determine the best process parameters, and guide the subsequent industrial scale-up process. It can be applied to fermentation process optimization, high-throughput strain screening, culture-medium screening and evaluation, etc.
The original AFDP chip module can realize the high-speed parallel transmission control of data and ensure the high consistency of parameters in each reactor. At the same time, the system can be expanded from a single bioreactor system to multiple bioreactor systems. The system also includes a series of well-designed desktop modules and intuitive software control modules, extremely convenient.
Optimization of fermentation process of strain
The key factors affecting fermentation (agitation, temperature, pH, dissolved oxygen, etc.) can be found out in a short time by using parallel bioreactor to simulate the production process.
Screening of high throughput strains by fixation process
Under the existing production process system (raw material, feed, temperature, dissolved oxygen and other parameters are determined), a large number of newly constructed engineering strains can be quickly screened by using parallel bioreactor, and the target strains of the process can be quickly obtained for large-scale production.
Culture-medium screening and evaluation
The use of parallel bioreactor can evaluate the consistency of raw materials from different batches, different origins and different sources, and find out the optimal ratio of late fermentation, which is conducive to the amplification of production.
Miniaturization
The whole machine is compact, integrated design, saving laboratory space; and production tanks in the structure, flow field characteristics and control methods to maintain consistency, easy to enlarge later.
Convenience
All-in-one design, plug-and-play; easy to learn and easy to operate, clear logo, dummy-proof design.
Refinement
Independent control with 41 hardware measurement and control parameters and 192 software parameters per tank. The structure is consistent with the production tanks and easy to enlarge.
Platforming
Arbitrary expansion of multiple devices to form a highthroughput fermentation platform; grouping of fermenters across devices; cross-device parallelism
One-touch calibration
pH, DO, temperature, and charge pump flow rate can be quickly calibrated with one click, and data is displayed visually.
Time-sharing control
It can be pre-programmed and timed for automatic parameter regulation.
AFDP control
The hardware ensures the synchronization of signal acquisition and command sending, reduces the size by more than 50 times, is plug-and-play, and is easily extended by third-party devices.
One button operation
Convenient control between multiple parallel bioreactors can be realized, with one key to select tank number and one key to set parameters.
Automatic compensation function
pH and DO have automatic compensation adjustment.
Pump free conversion
Acid and alkali pump can be used as feed pump, pH not only has two-way automatic control mode, and one-way alkali and one-way acid mode.
MGC
Microbial growth curve analyzer.
Microbial growth curve analyzer MGC-200 series is a fully automated instrument that can achieve real-time detection of microbial growth status under different growth temperatures, different media compositions and different light combinations, and automatically draw growth curves, providing a powerful aid for microbial research.
The whole process does not require personnel to guard, no frequent sampling, completely eliminate the risk of pollution, and truly free up manpower.
Escherichia coli is one of the most common microorganisms in the laboratory, belonging to Gram-negative short bacillus, the size of 0.5×1~3μm, periflagellate, motility, no spore.
E. coli growth curve
(Culture temperature 36℃, 96-well plate, culture volume 200μL, culture time 24hr, interval time 10min)
Schizomyces is a typical biological model of cell division, which is widely used in cell biology research. The size of schizomyces is 4~5×8~15μm, it is easy to settle, and requires high rotational speed to mix.
Growth curve of schizogenetic yeast
(Culture temperature 30℃, 48 well plate, culture volume 500μL, culture time 24hr, interval time 30min)
Lactobacillus rhamnosus is a kind of gram-positive probiotics with anaerobic acid resistance and no spore production. The size of Lactobacillus rhamnosus is 0.8~1.0×2~4μm. It is usually cultured in standing position and easy to agglomerate.
Growth curve of Lactobacillus rhamnosus
(Culture temperature 37℃, 12-well plate, culture volume 2400μL, culture time 72hr, interval time 30min)
Lactobacillus plantarum is a kind of lactic acid bacteria, anaerobic or facultative anaerobic, larger than 0.9~1.2×3~8μm, Trichoides cylindricus. Usually lacking flagella, but capable of locomotion. Gram positive, no spore.
Growth curve of Lactobacillus plantarum
(Culture temperature 37℃, 12-well plate, culture volume 2400μL, culture time 24hr, interval time 30min)
Accurate full spectrum detection
The advanced full-spectrum detection technology, without replacing the filter, can simultaneously detect the absorbance of any number of wavelengths in the range of 300~850, providing a solution for a variety of biomass quantitative detection.
High speed oscillation
The maximum vibration speed can reach 1250rpm, so that the small volume of liquid can be fully mixed, and the microbial vibration culture in the 96-well plate can be realized.
High flux
With two culture plates, multiple adapters compatible with different sizes of culture plates, up to 192 samples can be processed simultaneously.
High energy long life xenon lamp
Xenon lamp as a light source has the advantages of high energy, no preheating, to lay the foundation for high resolution, high sensitivity, rapid detection, at the same time, the light source is good stability, long life, no frequent replacement.
Full spectral scan
It can realize full spectrum scanning in the wavelength range of 300-850nm, and analyze the best wavelength suitable for the sample to be measured.
Advanced denoising algorithm
The optimized algorithm removes background noise and obtains more accurate growth curve.
Illumination function
With RGBW four-color light setting function, it can be used to study the influence of light factors such as light period, light wavelength and light intensity on algae growth.
High precision temperature control
With a hot cover anti-condensation design, with refrigeration and heating modules, at room temperature conditions (25℃) temperature control range of 15-60℃. The temperature can be changed in the middle of microbial culture to facilitate the accumulation of specific metabolites.
Easy to use operating system
With standard preset program, simple operation, convenient data processing. At the same time, customers can customize templates for personalized operation Settings and data analysis.
More
Wide range of application
A variety of microorganisms, including bacteria, fungi, yeast, phage, amoeba and algae, can be monitored and cultured online.
Multiple application scenarios
· Measure the compound effects of different factors on microorganisms, such as pH and temperature，Degree, water activity, salinity, chemicals, etc
· The contents of vitamins, amino acids, antibiotics, disinfectants, toxins, biostimulants and growth blockers were measured by biological method
· Continuously report growth parameters in multiple cultures
· Optimization of biodegradation conditions for pollutants
· Study the metabolic process of microorganisms
· Study phage growth dynamics curve
· Measure the number of viable microorganisms in food
· Research on yeast and other strains
· Develop new antimicrobial agents
· Improvement of SCP production process of microbial single-cell protein
· Study the production of enzymes, proteins, fatty acids or other substances in the production process of yogurt, wine and food
· Improved water treatment, biofilm and activated sludge treatment processes
· Study the influence of different temperatures on microbial processes
· Determine the minimum inhibitory concentration of the antimicrobial agent
· Determine the minimum lethal dose of antibiotics or other compounds
· Determine the toxicity and potential mutagenicity of different substances
· LAL test of endotoxin
· Make mathematical models of microbial, phage and cell growth
· Develop characteristic microorganisms
· Develop selective and non-selective culture-medium for microorganisms and cells
· Bacterial urine detection
· Testing of microbial preservatives
Faster
Effective liberation of manpower
1. Automatic measurement to avoid staying up late;
2.Automatic curve drawing, reducing complicated calculation drawing;
Better
Process safety and accurate results
1. Closed culture and detection can ensure that the samples are not contaminated and the experimental environment is safe;
2. There is no need for sampling and testing. Compared with sampling and testing, the experimental results are more accurate without loss of samples;
Save
Save reagents and consumables
Save more than 50% reagent;
Save 90% of the suction head;
Save 100% on Petri dishes;
Post time: Mar-23-2023
